Introduction
Posaconazole is a second-generation triazole antifungal drug. Compared with other triazole drugs, it has the advantages of wider antibacterial spectrum, high antibacterial activity, and good safety and tolerance. It is widely used for Candida and Aspergillus. Prevention and treatment of and treatment of Mucor.
Posaconazole main ingredient structural formula
Posaconazole oral suspension prepared by ATS
Process:
First prepare the suspension (which can be cut by a shear first), and then use ATS high-pressure microjet to control its particle size within the required range.
Difficulties in preparation:
Posa particles are relatively hard and difficult to homogenize into particles of the required size.
Solution:
For particles that are difficult to crush, ATS specially designed homogenization equipment requires less homogenization and has better results.
Result:
After homogenization, the particle size becomes smaller and the distribution is more uniform!