Yeast has a relatively complete gene expression regulation mechanism and the ability to process and modify expression products. Saccharomyces.Cerevisiae was first recognized in molecular genetics and was also the first yeast host for foreign gene expression. The foreign gene expression system using Pichia pastoris as the host has developed most rapidly in recent years and is also the most widely used.
High-pressure homogenization is the most common method of cell disruption in biopharmaceutical processes. Lysis in a homogenizer relies on pumping the cell slurry through a restrictive pore valve. Cells suspended in spent culture medium or buffer obtained from the bioreactor step are conveyed through the product supply line to a plunger pump, which moves the cell slurry to homogenization at pressures up to >1,000 bar (14,500 psi) machine valve.
ATS provides equipment of various specifications from experiments to large-scale production (up to 4000L/H) to meet the needs of customers at different stages.

● High crushing rate, more than 95% can be broken at one time
● Special feed valve design, no exhaust required, direct feeding
● Built-in cooling system directly absorbs the heat generated by crushing to ensure the activity of intracellular substances
● Variable frequency control system can adjust the flow rate according to requirements
● Comply with GMP design and pass EU CE certification
● PLC control screen makes operation easier
Broken example

Yeast 800bar 2 times result