01 ceramide
Ceramide is a lipid that makes up about 40-50% of this lipid matrix in healthy skin. The other components are
cholesterol (about 25%) and free fatty acids (10-15%). It can form a waterproof barrier on the skin surface,
which can not only help the skin to lock in water, bear the role of protecting the skin and moisturizing,
moisturizing, etc., but also promote the skin barrier to self-repair, protect the skin from external stimulation and
other functions, but the secretion of ceramide in the skin will decrease with age, thereby causing a series of
problems such as dry, aging, rough skin.
02 Application difficulties
Ceramide has a high melting point, low solubility, and is easy to crystallize or flocculate from cosmetic formulas,
which not only affects the stability of the formula, but also reduces the utilization rate of ceramide, greatly limiting
its application.
03 Nano liposome coated ceramide technology
ATS uses high pressure homogenization and nano liposome encapsulation technology to wrap ceramide in nano
liposome, which solves the problems of solubility and applicability well and improves the availability.
Advantages of liposomes:
Transdermal: The liposome has a high degree of biocompatibility with the lipid of the skin stratum corneum,
which realizes the transdermal absorption of the effective ingredients.
Slow release: The drug with liposome as the carrier is easily absorbed in the epidermal layer and dermis layer,
forming a drug reservoir, and the drug can be released continuously.
Repairability: Even if there is no liposome that encapsulates the active substance, it can inhibit water loss in the
deep skin; At the same time, repair the damaged human cell membrane and provide phospholipids for the phospholipid
bilayer of the new cell membrane.
Protection: By encapsulating the active ingredient in liposomes, the active ingredient is isolated from the external
environment to improve the stability of the active substance.
** ** : Liposomes are formed from natural substances and are non-toxic, degradable and non-immunogenic.
The size of the ceramide liposomes prepared by ATS was uniform and the state was stable.